Rx Prescription Only
PABVIT-K27 Softgel
CapsulesCalcitriol, Calcium Citrate Malate, Vitamin K2-7, Methylcobalamin, Zinc, Magnesium & L-Methyl Folate Soft Gelatin Capsules
PABVIT-K27 is a scientifically formulated multi-nutrient softgel capsule combining seven essential vitamins and minerals that work in synergy to support bone health, nerve function, and overall metabolic wellness. It brings together Calcitriol (the active form of Vitamin D), Calcium Citrate...
Pack Size
10×1×10 Softgel Capsules | 1×10 Softgel Capsules
Marketed By
Pab Pharma
Type
Prescription Medicine
Form
Soft Gelatin (Softgel) Capsules
Clinical Overview
PABVIT-K27 is a scientifically formulated multi-nutrient softgel capsule combining seven essential vitamins and minerals that work in synergy to support bone health, nerve function, and overall metabolic wellness. It brings together Calcitriol (the active form of Vitamin D), Calcium Citrate Malate, Vitamin K2-7, Methylcobalamin (Vitamin B12), Zinc, Magnesium, and L-Methyl Folate — a comprehensive combination addressing the nutritional gaps that commonly lead to weakened bones, nerve damage, and deficiency-related conditions. PABVIT-K27 is particularly beneficial for individuals with calcium and vitamin D deficiencies, post-menopausal women at risk of osteoporosis, the elderly, pregnant women, and anyone requiring comprehensive bone and nerve nutritional support.Composition
| Ingredient | Strength | Class |
|---|---|---|
| Calcitriol (Active Vitamin D3) | Calcium absorption & bone mineralization | - |
| Calcium Citrate Malate | Highly bioavailable calcium for bones & teeth | - |
| Vitamin K2-7 (MK-7) | Directs calcium to bones; prevents arterial calcification | - |
| Methylcobalamin (Vitamin B12) | Nerve health, DNA synthesis, red blood cell formation | - |
| Zinc | Immune function, wound healing, bone metabolism | - |
| Magnesium | Bone density, muscle function, nerve transmission | - |
| L-Methyl Folate | Active form of Folate; DNA repair, homocysteine regulation | - |
What Is PABVIT-K27 Softgel Used For?
PABVIT-K27 Softgel is primarily used for the treatment and management of:
- PABVIT-K27 is recommended for the prevention and management of:
- Calcium & Vitamin D Deficiency — Including rickets in children and osteomalacia (soft bones) in adults
- Osteoporosis — Thinning and weakening of bones, especially in post-menopausal women and the elderly
- Osteopenia — Early-stage bone density loss before full osteoporosis develops
- Vitamin B12 Deficiency — Leading to fatigue, weakness, numbness, tingling, and anemia
- Neuropathy (Nerve Damage) — Pain, tingling, or numbness in hands and feet due to nerve damage
- Folate Deficiency — Associated with anemia, neural tube defects (in pregnancy), and elevated homocysteine
- Hypomagnesemia — Low magnesium levels causing muscle cramps, spasms, and weakness
- Zinc Deficiency — Impaired immunity, slow wound healing, and poor skin health
- Pregnancy & Lactation Support — Meeting the increased demands for calcium, folate, B12, and other nutrients during pregnancy
- General Bone & Joint Health Maintenance — For adults at risk of age-related bone loss
How Does PABVIT-K27 Softgel Work?
How PABVIT-K27 Softgel Works – Simple Explanation :
Calcitriol (Active Vitamin D3) — -
- Each ingredient in PABVIT-K27 has a specific, targeted role, and they work best together: Calcitriol (Active Vitamin D3) Calcitriol is the biologically active form of Vitamin D, and it is far more potent than the regular Vitamin D3 (Cholecalciferol) found in most supplements. While regular Vitamin D3 must be converted by the liver and kidneys before it can be used, Calcitriol is ready to act immediately. It increases the absorption of calcium and phosphorus from the intestines, promotes calcium reabsorption in the kidneys, and is essential for proper bone mineralisation. Calcitriol is particularly recommended for patients with kidney disease, where the conversion of regular Vitamin D is impaired.
Calcium Citrate Malate — -
- Calcium Citrate Malate This is one of the most bioavailable forms of calcium available — significantly better absorbed than calcium carbonate, especially in individuals with low stomach acid (common in the elderly and those on acid-reducing medicines). Calcium Citrate Malate does not require stomach acid for absorption and can be taken regardless of meals, making it ideal for a wide range of patients. Calcium is the primary mineral that gives bones their strength and rigidity.
Vitamin K2-7 (MK-7) — -
- Vitamin K2-7 (Menaquinone-7 / MK-7) Vitamin K2-7 is the "calcium traffic controller" of the body. It activates two critical proteins — Osteocalcin, which binds calcium into bone tissue, and Matrix Gla Protein (MGP), which prevents calcium from depositing in arteries and soft tissues. Without adequate K2, calcium absorbed through Calcitriol may be deposited in blood vessels rather than bones — a risk factor for cardiovascular disease. K2-7 (MK-7) is the preferred form due to its long half-life and superior bioavailability compared to K2-4.
Methylcobalamin (Vitamin B12) — -
- Methylcobalamin (Vitamin B12) Methylcobalamin is the active, neurologically available form of Vitamin B12. Unlike Cyanocobalamin (the synthetic form), Methylcobalamin is directly usable by the nervous system without any conversion. It supports the formation of myelin sheath — the protective covering of nerve fibres — and is essential for the repair and regeneration of damaged nerves. It also plays a key role in DNA synthesis, red blood cell production, and reducing homocysteine levels (elevated homocysteine is linked to heart disease and bone loss).
Zinc — -
- Zinc Zinc is essential for bone formation and bone remodelling. It stimulates the activity of osteoblasts (bone-forming cells) and inhibits osteoclasts (bone-resorbing cells). Zinc also supports immune function, skin integrity, wound healing, and plays a critical role in DNA repair and cell division. Deficiency is associated with poor growth, weakened immunity, and slow healing.
Magnesium — -
- Magnesium Magnesium is a cofactor for over 300 enzymatic reactions in the body. About 60% of the body's magnesium is stored in bone. It plays a vital role in activating Vitamin D (Calcitriol requires magnesium to function), regulating calcium transport, and maintaining bone density. Magnesium also supports muscle function, nerve transmission, and energy production. Deficiency leads to muscle cramps, weakness, and increased bone fragility.
L-Methyl Folate — -
- L-Methyl Folate L-Methyl Folate (5-MTHF) is the biologically active form of Folic Acid, able to cross the blood-brain barrier and be directly utilised by cells without requiring enzymatic conversion. It supports DNA synthesis, cell division, and red blood cell formation. Crucially during pregnancy, it prevents neural tube defects in the developing foetus. It also works with Methylcobalamin and B6 to lower homocysteine — an amino acid that in excess can damage blood vessels and reduce bone density.
Dosage & How to Take
- Dose: As directed by the Physician.
- Route: Oral (by mouth)
- General Guidance:
- Typically taken once daily, preferably with or after a meal to enhance absorption of fat-soluble vitamins (Calcitriol and K2-7).
- Swallow the softgel capsule whole with water.
- For best results, take consistently at the same time each day.
- Duration of supplementation is determined by your doctor based on blood levels and clinical condition.
- Important: Calcitriol is an active hormone and must only be taken at the prescribed dose. Do not increase the dose without medical supervision.
Important: Dosage and duration are determined by your doctor based on your age, weight, and medical condition. Always follow your physician's instructions.
Possible Side Effects
PABVIT-K27 is generally well-tolerated at recommended doses. Possible side effects include:
Common (may affect up to 1 in 10 people):
- With Calcitriol (if dose is too high — Hypercalcemia):
- Nausea, vomiting, or loss of appetite
- Excessive thirst and frequent urination
- Weakness or fatigue
- Constipation
- Headache
- Confusion or disorientation (in severe cases)
Less Common:
- Mild stomach upset or nausea (usually resolves with food)
- Diarrhoea or constipation (more common with higher calcium doses)
- Allergic skin reactions (rare)
- If you experience signs of high calcium (hypercalcemia) — excessive thirst, urinating more than usual, confusion, muscle weakness — stop the medicine and consult your doctor immediately.
Rare but Serious (seek immediate medical attention):
- Information not provided.
Precautions & Warnings
Before taking PABVIT-K27 Softgel, inform your doctor if you:
- Before taking PABVIT-K27, inform your doctor if you:
- Have kidney stones or a history of kidney disease
- Have hypercalcemia (already high blood calcium levels)
- Have hypervitaminosis D (excess Vitamin D)
- Are on blood-thinning medicines (Warfarin/Coumadin) — Vitamin K2 may interact
- Have sarcoidosis or other granulomatous diseases
- Are taking thiazide diuretics
- Are pregnant or breastfeeding (while L-Methyl Folate and calcium are beneficial in pregnancy, Calcitriol dose must be carefully monitored)
Special Warnings:
- Calcitriol can cause hypercalcemia if taken in excess — regular blood calcium monitoring is advised for long-term use
- Adequate hydration should be maintained while taking calcium supplements
- Do not take additional calcium or Vitamin D supplements without informing your doctor, to avoid toxicity
Drug Interactions
Inform your doctor about all medications you are currently taking. PABVIT-K27 Softgel may interact with:
Always consult a healthcare professional before combining medications.
Storage Instructions
- Store in a cool and dry place
- Protect from direct sunlight and heat
- Store at room temperature, away from moisture
- Keep the medicine out of reach of children
- Do not use after the expiry date printed on the pack
Why Choose PABVIT-K27 Softgel?
- 7-in-1 comprehensive formula — covers bone, nerve, immune, and metabolic health in one softgel
- Calcitriol vs. regular Vitamin D3 — Uses the active form, offering superior efficacy especially in kidney-compromised patients
- Calcium Citrate Malate — Better absorbed than Calcium Carbonate, works without needing stomach acid
- Vitamin K2-7 (MK-7) — Ensures calcium goes to bones, not arteries
- Active B12 (Methylcobalamin) — Directly supports nerves without conversion
- Active Folate (L-Methyl Folate) — Superior to standard folic acid, works even in patients with MTHFR gene variants
- Softgel formulation — Enhanced absorption of fat-soluble nutrients (Calcitriol, K2-7)
- Trusted by PAB PHARMA for patients with osteoporosis, neuropathy, deficiency states, and pregnancy support
Frequently Asked Questions
Regular supplements use Cholecalciferol (Vitamin D3), which still needs to be converted by the liver and kidneys. PABVIT-K27 uses Calcitriol — the final active form — which is directly effective. Additionally, PABVIT-K27 includes Vitamin K2-7 (which most regular supplements lack) to ensure calcium is directed to bones rather than arteries.
You must inform your doctor before taking PABVIT-K27, as Vitamin K2 can interact with Warfarin and may require a dose adjustment.
It contains L-Methyl Folate, Calcium, and Methylcobalamin that are beneficial during pregnancy. However, Calcitriol must be carefully dosed during pregnancy — always use only as prescribed by your doctor.
Improvement in Vitamin D and calcium deficiency symptoms is typically seen within 4–8 weeks. Bone density improvements with long-term supplementation are assessed over 6–12 months.
It is better taken with food, as Calcitriol and Vitamin K2-7 are fat-soluble vitamins and their absorption is enhanced in the presence of dietary fat.
This formulation contains Calcitriol, which is a potent active hormone. Paediatric use should only be under the direct supervision of a doctor with appropriate dosing.